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Autoantigen microarrays reveal autoantibodies associated with proliferative nephritis and active disease in pediatric systemic lupus erythematosus

INTRODUCTION: Pediatric systemic lupus erythematosus (pSLE) patients often initially present with more active and severe disease than adults, including a higher frequency of lupus nephritis. Specific autoantibodies, including anti-C1q, anti-DNA and anti-alpha-actinin, have been associated with kidne...

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Detalles Bibliográficos
Autores principales: Haddon, D. James, Diep, Vivian K., Price, Jordan V., Limb, Cindy, Utz, Paul J., Balboni, Imelda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493823/
https://www.ncbi.nlm.nih.gov/pubmed/26081107
http://dx.doi.org/10.1186/s13075-015-0682-6