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Panax Notoginseng flower saponins (PNFS) inhibit LPS-stimulated NO overproduction and iNOS gene overexpression via the suppression of TLR4-mediated MAPK/NF-kappa B signaling pathways in RAW264.7 macrophages
BACKGROUND: Panax Notoginseng flower saponins (PNFS) are the main active component of Panax notoginseng (Burk) F. H. Chen flower bud (PNF) and possess significant anti-inflammatory efficacy. This study aims to explore the mechanisms underlying PNFS’ antiflammatory action in RAW264.7 macrophages. MET...
Autores principales: | Peng, Xiao-Xu, Zhang, Shu-Hui, Wang, Xiao-Ling, Ye, Ting-Jie, Li, Hua, Yan, Xiao-Feng, Wei, Li, Wu, Zhong-Ping, Hu, Jing, Zou, Chun-Pu, Wang, You-Hua, Hu, Xu-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493833/ https://www.ncbi.nlm.nih.gov/pubmed/26155304 http://dx.doi.org/10.1186/s13020-015-0045-x |
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