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Intracellular spermine prevents acid-induced uncoupling of Cx43 gap junction channels

Polyamines (PAs), such as spermine and spermidine, modulate the activity of numerous receptors and channels in the central nervous system (CNS) and are stored in glial cells; however, little attention has been paid to their role in the regulation of connexin (Cx)-based gap junction channels. We have...

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Detalles Bibliográficos
Autores principales: Skatchkov, Serguei N., Bukauskas, Feliksas F., Benedikt, Jan, Inyushin, Mikhail, Kucheryavykh, Yuriy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493885/
https://www.ncbi.nlm.nih.gov/pubmed/26011388
http://dx.doi.org/10.1097/WNR.0000000000000385

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