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Structures of actin-like ParM filaments show architecture of plasmid-segregating spindles

Active segregation of E. coli low-copy number plasmid R1 involves formation of a bipolar spindle made of left-handed double-helical actin-like ParM filaments (1-6). ParR links the filaments with centromeric parC plasmid DNA, while facilitating the addition of subunits to ParM filaments (3,7-9). Grow...

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Detalles Bibliográficos
Autores principales: Bharat, Tanmay A.M., Murshudov, Garib N., Sachse, Carsten, Löwe, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493928/
https://www.ncbi.nlm.nih.gov/pubmed/25915019
http://dx.doi.org/10.1038/nature14356