Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-d-Glucose Uptake in Prostate Cancer Mouse Xenografts

PURPOSE: Prostate cancer (PCa) is the second most common cause of cancer-related death among men in the United States. Due to the lipid-driven metabolic phenotype of PCa, imaging with 2-deoxy-2-[(18)F]fluoro-d-glucose ([(18)F]FDG) is suboptimal, since tumors tend to have low avidity for glucose. PRO...

Descripción completa

Detalles Bibliográficos
Autores principales: Schlaepfer, Isabel R., Glodé, L. Michael, Hitz, Carolyn A., Pac, Colton T., Boyle, Kristen E., Maroni, Paul, Deep, Gagan, Agarwal, Rajesh, Lucia, Scott M., Cramer, Scott D., Serkova, Natalie J., Eckel, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493937/
https://www.ncbi.nlm.nih.gov/pubmed/25561013
http://dx.doi.org/10.1007/s11307-014-0814-4

Ejemplares similares

Ejemplares similares