Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves

Although Schwann cell myelin breakdown is the universal outcome of a remarkably wide range of conditions that cause disease or injury to peripheral nerves, the cellular and molecular mechanisms that make Schwann cell–mediated myelin digestion possible have not been established. We report that Schwan...

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Detalles Bibliográficos
Autores principales: Gomez-Sanchez, Jose A., Carty, Lucy, Iruarrizaga-Lejarreta, Marta, Palomo-Irigoyen, Marta, Varela-Rey, Marta, Griffith, Megan, Hantke, Janina, Macias-Camara, Nuria, Azkargorta, Mikel, Aurrekoetxea, Igor, De Juan, Virginia Gutiérrez, Jefferies, Harold B.J., Aspichueta, Patricia, Elortza, Félix, Aransay, Ana M., Martínez-Chantar, María L., Baas, Frank, Mato, José M., Mirsky, Rhona, Woodhoo, Ashwin, Jessen, Kristján R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494002/
https://www.ncbi.nlm.nih.gov/pubmed/26150392
http://dx.doi.org/10.1083/jcb.201503019

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