Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function

Pericentriolar material (PCM) mediates the microtubule (MT) nucleation and anchoring activity of centrosomes. A scaffold organized by Centrosomin (Cnn) serves to ensure proper PCM architecture and functional changes in centrosome activity with each cell cycle. Here, we investigate the mechanisms tha...

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Detalles Bibliográficos
Autores principales: Lerit, Dorothy A., Jordan, Holly A., Poulton, John S., Fagerstrom, Carey J., Galletta, Brian J., Peifer, Mark, Rusan, Nasser M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494003/
https://www.ncbi.nlm.nih.gov/pubmed/26150390
http://dx.doi.org/10.1083/jcb.201503117

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