Myelinophagy: Schwann cells dine in

When nerve injury occurs, the axon and myelin fragments distal to the injury site have to be cleared away before repair. In this issue, Gomez-Sanchez et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/jcb.201503019) find that clearance of the damaged myelin within Schwann cells occurs not by phag...

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Detalles Bibliográficos
Autores principales: Thumm, Michael, Simons, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494007/
https://www.ncbi.nlm.nih.gov/pubmed/26150387
http://dx.doi.org/10.1083/jcb.201506039
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author Thumm, Michael
Simons, Mikael
author_facet Thumm, Michael
Simons, Mikael
author_sort Thumm, Michael
collection PubMed
description When nerve injury occurs, the axon and myelin fragments distal to the injury site have to be cleared away before repair. In this issue, Gomez-Sanchez et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/jcb.201503019) find that clearance of the damaged myelin within Schwann cells occurs not by phagocytosis but rather via selective autophagy, in a process they term “myelinophagy.”
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spelling pubmed-44940072016-01-06 Myelinophagy: Schwann cells dine in Thumm, Michael Simons, Mikael J Cell Biol Reviews When nerve injury occurs, the axon and myelin fragments distal to the injury site have to be cleared away before repair. In this issue, Gomez-Sanchez et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/jcb.201503019) find that clearance of the damaged myelin within Schwann cells occurs not by phagocytosis but rather via selective autophagy, in a process they term “myelinophagy.” The Rockefeller University Press 2015-07-06 /pmc/articles/PMC4494007/ /pubmed/26150387 http://dx.doi.org/10.1083/jcb.201506039 Text en © 2015 Thumm and Simons This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Thumm, Michael
Simons, Mikael
Myelinophagy: Schwann cells dine in
title Myelinophagy: Schwann cells dine in
title_full Myelinophagy: Schwann cells dine in
title_fullStr Myelinophagy: Schwann cells dine in
title_full_unstemmed Myelinophagy: Schwann cells dine in
title_short Myelinophagy: Schwann cells dine in
title_sort myelinophagy: schwann cells dine in
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494007/
https://www.ncbi.nlm.nih.gov/pubmed/26150387
http://dx.doi.org/10.1083/jcb.201506039
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