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Chronic Stress and Adolescents’ Mental Health: Modifying Effects of Basal Cortisol and Parental Psychiatric History. The TRAILS Study

Large individual differences in adolescent mental health following chronic psychosocial stress suggest moderating factors. We examined two established moderators, basal cortisol and parental psychiatric history, simultaneously. We hypothesized that individuals with high basal cortisol, assumed to in...

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Autores principales: Zandstra, Anna Roos E., Hartman, Catharina A., Nederhof, Esther, van den Heuvel, Edwin R., Dietrich, Andrea, Hoekstra, Pieter J., Ormel, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494132/
https://www.ncbi.nlm.nih.gov/pubmed/25617009
http://dx.doi.org/10.1007/s10802-014-9970-x
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author Zandstra, Anna Roos E.
Hartman, Catharina A.
Nederhof, Esther
van den Heuvel, Edwin R.
Dietrich, Andrea
Hoekstra, Pieter J.
Ormel, Johan
author_facet Zandstra, Anna Roos E.
Hartman, Catharina A.
Nederhof, Esther
van den Heuvel, Edwin R.
Dietrich, Andrea
Hoekstra, Pieter J.
Ormel, Johan
author_sort Zandstra, Anna Roos E.
collection PubMed
description Large individual differences in adolescent mental health following chronic psychosocial stress suggest moderating factors. We examined two established moderators, basal cortisol and parental psychiatric history, simultaneously. We hypothesized that individuals with high basal cortisol, assumed to indicate high context sensitivity, would show relatively high problem levels following chronic stress, especially in the presence of parental psychiatric history. With Linear Mixed Models, we investigated the hypotheses in 1917 Dutch adolescents (53.2 % boys), assessed at ages 11, 13.5, and 16. Low basal cortisol combined with the absence of a parental psychiatric history increased the risk of externalizing but not internalizing problems following chronic stress. Conversely, low basal cortisol combined with a substantial parental psychiatric history increased the risk of internalizing but not externalizing problems following chronic stress. Thus, parental psychiatric history moderated stress- cortisol interactions in predicting psychopathology, but in a different direction than hypothesized. We conclude that the premise that basal cortisol indicates context sensitivity may be too crude. Context sensitivity may not be a general trait but may depend on the nature of the context (e.g., type or duration of stress exposure) and on the outcome of interest (e.g., internalizing vs. externalizing problems). Although consistent across informants, our findings need replication. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s10802-014-9970-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-44941322015-07-08 Chronic Stress and Adolescents’ Mental Health: Modifying Effects of Basal Cortisol and Parental Psychiatric History. The TRAILS Study Zandstra, Anna Roos E. Hartman, Catharina A. Nederhof, Esther van den Heuvel, Edwin R. Dietrich, Andrea Hoekstra, Pieter J. Ormel, Johan J Abnorm Child Psychol Article Large individual differences in adolescent mental health following chronic psychosocial stress suggest moderating factors. We examined two established moderators, basal cortisol and parental psychiatric history, simultaneously. We hypothesized that individuals with high basal cortisol, assumed to indicate high context sensitivity, would show relatively high problem levels following chronic stress, especially in the presence of parental psychiatric history. With Linear Mixed Models, we investigated the hypotheses in 1917 Dutch adolescents (53.2 % boys), assessed at ages 11, 13.5, and 16. Low basal cortisol combined with the absence of a parental psychiatric history increased the risk of externalizing but not internalizing problems following chronic stress. Conversely, low basal cortisol combined with a substantial parental psychiatric history increased the risk of internalizing but not externalizing problems following chronic stress. Thus, parental psychiatric history moderated stress- cortisol interactions in predicting psychopathology, but in a different direction than hypothesized. We conclude that the premise that basal cortisol indicates context sensitivity may be too crude. Context sensitivity may not be a general trait but may depend on the nature of the context (e.g., type or duration of stress exposure) and on the outcome of interest (e.g., internalizing vs. externalizing problems). Although consistent across informants, our findings need replication. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s10802-014-9970-x) contains supplementary material, which is available to authorized users. Springer US 2015-01-25 2015 /pmc/articles/PMC4494132/ /pubmed/25617009 http://dx.doi.org/10.1007/s10802-014-9970-x Text en © The Author(s) 2015 https://creativecommons.org/licenses/by/4.0/ Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Article
Zandstra, Anna Roos E.
Hartman, Catharina A.
Nederhof, Esther
van den Heuvel, Edwin R.
Dietrich, Andrea
Hoekstra, Pieter J.
Ormel, Johan
Chronic Stress and Adolescents’ Mental Health: Modifying Effects of Basal Cortisol and Parental Psychiatric History. The TRAILS Study
title Chronic Stress and Adolescents’ Mental Health: Modifying Effects of Basal Cortisol and Parental Psychiatric History. The TRAILS Study
title_full Chronic Stress and Adolescents’ Mental Health: Modifying Effects of Basal Cortisol and Parental Psychiatric History. The TRAILS Study
title_fullStr Chronic Stress and Adolescents’ Mental Health: Modifying Effects of Basal Cortisol and Parental Psychiatric History. The TRAILS Study
title_full_unstemmed Chronic Stress and Adolescents’ Mental Health: Modifying Effects of Basal Cortisol and Parental Psychiatric History. The TRAILS Study
title_short Chronic Stress and Adolescents’ Mental Health: Modifying Effects of Basal Cortisol and Parental Psychiatric History. The TRAILS Study
title_sort chronic stress and adolescents’ mental health: modifying effects of basal cortisol and parental psychiatric history. the trails study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494132/
https://www.ncbi.nlm.nih.gov/pubmed/25617009
http://dx.doi.org/10.1007/s10802-014-9970-x
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