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Increasing the Vaccine Potential of Live M. bovis BCG by Coadministration with Plasmid DNA Encoding a Tuberculosis Prototype Antigen
The attenuated live M. bovis Bacille-Calmette-Guérin (BCG) is still the sole vaccine used against tuberculosis, but confers only variable efficacy against adult pulmonary tuberculosis (TB). Though no clear explanation for this limited efficacy has been given, different hypotheses have been advanced,...
Autores principales: | Bruffaerts, Nicolas, Romano, Marta, Denis, Olivier, Jurion, Fabienne, Huygen, Kris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494193/ https://www.ncbi.nlm.nih.gov/pubmed/26344474 http://dx.doi.org/10.3390/vaccines2010181 |
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