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DNA-Encoded Flagellin Activates Toll-Like Receptor 5 (TLR5), Nod-like Receptor Family CARD Domain-Containing Protein 4 (NRLC4), and Acts as an Epidermal, Systemic, and Mucosal-Adjuvant

Eliciting effective immune responses using non-living/replicating DNA vaccines is a significant challenge. We have previously shown that ballistic dermal plasmid DNA-encoded flagellin (FliC) promotes humoral as well as cellular immunity to co-delivered antigens. Here, we observe that a plasmid encod...

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Detalles Bibliográficos
Autores principales:	Nyström, Sanna, Bråve, Andreas, Falkeborn, Tina, Devito, Claudia, Rissiek, Björn, Johansson, Daniel X., Schröder, Ulf, Uematsu, Satoshi, Akira, Shizuo, Hinkula, Jorma, Applequist, Steven E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494208/ https://www.ncbi.nlm.nih.gov/pubmed/26344341 http://dx.doi.org/10.3390/vaccines1040415

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