Doubly Phosphorylated Peptide Vaccines to Protect Transgenic P301S Mice against Alzheimer’s Disease Like Tau Aggregation

Intracellular neurofibrillary tangles and extracellular senile plaques are potential targets for active and passive immunotherapies. In this study we used the transgenic mouse model P301S for active immunizations with peptide vaccines composed of a double phosphorylated tau neoepitope (pSer202/pThr2...

Descripción completa

Detalles Bibliográficos
Autores principales: Richter, Monique, Mewes, Agneta, Fritsch, Manuela, Krügel, Ute, Hoffmann, Ralf, Singer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494214/
https://www.ncbi.nlm.nih.gov/pubmed/26344748
http://dx.doi.org/10.3390/vaccines2030601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494214/
https://www.ncbi.nlm.nih.gov/pubmed/26344748
http://dx.doi.org/10.3390/vaccines2030601

Ejemplares similares