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Caspase-1 Dependent IL-1β Secretion and Antigen-Specific T-Cell Activation by the Novel Adjuvant, PCEP
The potent adjuvant activity of the novel adjuvant, poly[di(sodiumcarboxylatoethylphenoxy)phosphazene] (PCEP), with various antigens has been reported previously. However, very little is known about its mechanisms of action. We have recently reported that intramuscular injection of PCEP induces NLRP...
Autores principales: | Awate, Sunita, Eng, Nelson F., Gerdts, Volker, Babiuk, Lorne A., Mutwiri, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494223/ https://www.ncbi.nlm.nih.gov/pubmed/26344742 http://dx.doi.org/10.3390/vaccines2030500 |
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