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Vaccinia Virus LC16m8∆ as a Vaccine Vector for Clinical Applications
The LC16m8 strain of vaccinia virus, the active ingredient in the Japanese smallpox vaccine, was derived from the Lister/Elstree strain. LC16m8 is replication-competent and has been administered to over 100,000 infants and 3,000 adults with no serious adverse reactions. Despite this outstanding safe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494248/ https://www.ncbi.nlm.nih.gov/pubmed/26344890 http://dx.doi.org/10.3390/vaccines2040755 |