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A Recombinant Raccoon Poxvirus Vaccine Expressing both Yersinia pestis F1 and Truncated V Antigens Protects Animals against Lethal Plague

In previous studies, we demonstrated in mice and prairie dogs that simultaneous administration of two recombinant raccoon poxviruses (rRCN) expressing Yersinia pestis antigens (F1 and V307—a truncated version of the V protein) provided superior protection against plague challenge compared to individ...

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Detalles Bibliográficos
Autores principales: Rocke, Tonie E., Kingstad-Bakke, Brock, Berlier, Willy, Osorio, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494250/
https://www.ncbi.nlm.nih.gov/pubmed/26344891
http://dx.doi.org/10.3390/vaccines2040772