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Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity

DNA vaccine-induced immunity can be enhanced by the co-delivery of synthetic gene-encoding molecular adjuvants. Many of these adjuvants have included cytokines, chemokines or co-stimulatory molecules that have been demonstrated to enhance vaccine-induced immunity by increasing the magnitude or type...

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Detalles Bibliográficos
Autores principales: Shedlock, Devon J., Tingey, Colleen, Mahadevan, Lavanya, Hutnick, Natalie, Reuschel, Emma L., Kudchodkar, Sagar, Flingai, Seleeke, Yan, Jenny, Kim, Joseph J., Ugen, Kenneth E., Weiner, David B., Muthumani, Kar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494262/
https://www.ncbi.nlm.nih.gov/pubmed/26344618
http://dx.doi.org/10.3390/vaccines2020196