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Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner

BACKGROUND: Accumulating evidence suggests that breast cancer involves tumour-initiating cells (TICs), which play a role in initiation, metastasis, therapeutic resistance and relapse of the disease. Emerging drugs that target TICs are becoming a focus of contemporary research. Mitocans, a group of c...

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Detalles Bibliográficos
Autores principales:	Yan, Bing, Stantic, Marina, Zobalova, Renata, Bezawork-Geleta, Ayenachew, Stapelberg, Michael, Stursa, Jan, Prokopova, Katerina, Dong, Lanfeng, Neuzil, Jiri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494715/ https://www.ncbi.nlm.nih.gov/pubmed/25967547 http://dx.doi.org/10.1186/s12885-015-1394-7

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