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High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor
Accurate optical reporting of electrical activity in genetically defined neuronal populations is a long-standing goal in neuroscience. Here we describe Accelerated Sensor of Action Potentials 1 (ASAP1), a novel voltage sensor design in which a circularly permuted green fluorescent protein is inserte...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494739/ https://www.ncbi.nlm.nih.gov/pubmed/24755780 http://dx.doi.org/10.1038/nn.3709 |