The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin

ABSTRACT: A series of mono-alkylcarboxylic acid derivatives of tetraphenylporphyrin have been prepared. All the porphyrins were completely characterized by use of mass, (1)H NMR, UV–visible, and fluorescence spectroscopy. Experimental log P were determined by use of reversed-phase thin-layer chromat...

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Detalles Bibliográficos
Autores principales: Zięba, Grzegorz, Rojkiewicz, Marcin, Kozik, Violetta, Jarzembek, Krystyna, Jarczyk, Anna, Sochanik, Aleksander, Kuś, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494763/
https://www.ncbi.nlm.nih.gov/pubmed/26166859
http://dx.doi.org/10.1007/s00706-011-0586-3
Descripción
Sumario:ABSTRACT: A series of mono-alkylcarboxylic acid derivatives of tetraphenylporphyrin have been prepared. All the porphyrins were completely characterized by use of mass, (1)H NMR, UV–visible, and fluorescence spectroscopy. Experimental log P were determined by use of reversed-phase thin-layer chromatography with use of log P (Rekker). These porphyrins are potential photosensitizers in photodynamic therapy. GRAPHICAL ABSTRACT: [Image: see text].

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