Cargando…

The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin

ABSTRACT: A series of mono-alkylcarboxylic acid derivatives of tetraphenylporphyrin have been prepared. All the porphyrins were completely characterized by use of mass, (1)H NMR, UV–visible, and fluorescence spectroscopy. Experimental log P were determined by use of reversed-phase thin-layer chromat...

Descripción completa

Detalles Bibliográficos
Autores principales: Zięba, Grzegorz, Rojkiewicz, Marcin, Kozik, Violetta, Jarzembek, Krystyna, Jarczyk, Anna, Sochanik, Aleksander, Kuś, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494763/
https://www.ncbi.nlm.nih.gov/pubmed/26166859
http://dx.doi.org/10.1007/s00706-011-0586-3
_version_ 1782380147739983872
author Zięba, Grzegorz
Rojkiewicz, Marcin
Kozik, Violetta
Jarzembek, Krystyna
Jarczyk, Anna
Sochanik, Aleksander
Kuś, Piotr
author_facet Zięba, Grzegorz
Rojkiewicz, Marcin
Kozik, Violetta
Jarzembek, Krystyna
Jarczyk, Anna
Sochanik, Aleksander
Kuś, Piotr
author_sort Zięba, Grzegorz
collection PubMed
description ABSTRACT: A series of mono-alkylcarboxylic acid derivatives of tetraphenylporphyrin have been prepared. All the porphyrins were completely characterized by use of mass, (1)H NMR, UV–visible, and fluorescence spectroscopy. Experimental log P were determined by use of reversed-phase thin-layer chromatography with use of log P (Rekker). These porphyrins are potential photosensitizers in photodynamic therapy. GRAPHICAL ABSTRACT: [Image: see text].
format Online
Article
Text
id pubmed-4494763
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Springer Vienna
record_format MEDLINE/PubMed
spelling pubmed-44947632015-07-09 The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin Zięba, Grzegorz Rojkiewicz, Marcin Kozik, Violetta Jarzembek, Krystyna Jarczyk, Anna Sochanik, Aleksander Kuś, Piotr Monatsh Chem Original Paper ABSTRACT: A series of mono-alkylcarboxylic acid derivatives of tetraphenylporphyrin have been prepared. All the porphyrins were completely characterized by use of mass, (1)H NMR, UV–visible, and fluorescence spectroscopy. Experimental log P were determined by use of reversed-phase thin-layer chromatography with use of log P (Rekker). These porphyrins are potential photosensitizers in photodynamic therapy. GRAPHICAL ABSTRACT: [Image: see text]. Springer Vienna 2011-08-24 2012 /pmc/articles/PMC4494763/ /pubmed/26166859 http://dx.doi.org/10.1007/s00706-011-0586-3 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Original Paper
Zięba, Grzegorz
Rojkiewicz, Marcin
Kozik, Violetta
Jarzembek, Krystyna
Jarczyk, Anna
Sochanik, Aleksander
Kuś, Piotr
The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin
title The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin
title_full The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin
title_fullStr The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin
title_full_unstemmed The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin
title_short The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin
title_sort synthesis of new potential photosensitizers. 1. mono-carboxylic acid derivatives of tetraphenylporphyrin
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494763/
https://www.ncbi.nlm.nih.gov/pubmed/26166859
http://dx.doi.org/10.1007/s00706-011-0586-3
work_keys_str_mv AT ziebagrzegorz thesynthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT rojkiewiczmarcin thesynthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT kozikvioletta thesynthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT jarzembekkrystyna thesynthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT jarczykanna thesynthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT sochanikaleksander thesynthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT kuspiotr thesynthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT ziebagrzegorz synthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT rojkiewiczmarcin synthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT kozikvioletta synthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT jarzembekkrystyna synthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT jarczykanna synthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT sochanikaleksander synthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin
AT kuspiotr synthesisofnewpotentialphotosensitizers1monocarboxylicacidderivativesoftetraphenylporphyrin