Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates

ABSTRACT: New dimethyl benzoylcarbonohydrazonodithioates were obtained by CS(2) addition to arylcarboxylic acid hydrazides and methylation of the formed adduct. The new derivatives were tested for their activity against Mycobacterium tuberculosis. Some compounds exhibited high activity toward sensit...

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Autores principales: Gobis, Katarzyna, Foks, Henryk, Zwolska, Zofia, Augustynowicz-Kopeć, Ewa, Główka, Marek L., Olczak, Andrzej, Sabisz, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494766/
https://www.ncbi.nlm.nih.gov/pubmed/26166854
http://dx.doi.org/10.1007/s00706-011-0572-9
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author Gobis, Katarzyna
Foks, Henryk
Zwolska, Zofia
Augustynowicz-Kopeć, Ewa
Główka, Marek L.
Olczak, Andrzej
Sabisz, Michał
author_facet Gobis, Katarzyna
Foks, Henryk
Zwolska, Zofia
Augustynowicz-Kopeć, Ewa
Główka, Marek L.
Olczak, Andrzej
Sabisz, Michał
author_sort Gobis, Katarzyna
collection PubMed
description ABSTRACT: New dimethyl benzoylcarbonohydrazonodithioates were obtained by CS(2) addition to arylcarboxylic acid hydrazides and methylation of the formed adduct. The new derivatives were tested for their activity against Mycobacterium tuberculosis. Some compounds exhibited high activity toward sensitive and resistant strains. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-44947662015-07-09 Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates Gobis, Katarzyna Foks, Henryk Zwolska, Zofia Augustynowicz-Kopeć, Ewa Główka, Marek L. Olczak, Andrzej Sabisz, Michał Monatsh Chem Original Paper ABSTRACT: New dimethyl benzoylcarbonohydrazonodithioates were obtained by CS(2) addition to arylcarboxylic acid hydrazides and methylation of the formed adduct. The new derivatives were tested for their activity against Mycobacterium tuberculosis. Some compounds exhibited high activity toward sensitive and resistant strains. GRAPHICAL ABSTRACT: [Image: see text] Springer Vienna 2011-08-16 2011 /pmc/articles/PMC4494766/ /pubmed/26166854 http://dx.doi.org/10.1007/s00706-011-0572-9 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Original Paper
Gobis, Katarzyna
Foks, Henryk
Zwolska, Zofia
Augustynowicz-Kopeć, Ewa
Główka, Marek L.
Olczak, Andrzej
Sabisz, Michał
Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates
title Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates
title_full Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates
title_fullStr Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates
title_full_unstemmed Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates
title_short Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates
title_sort synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494766/
https://www.ncbi.nlm.nih.gov/pubmed/26166854
http://dx.doi.org/10.1007/s00706-011-0572-9
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