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HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells

Hypoxia-inducible factor 1α (HIF-1α) expression is a hallmark of intratumoral hypoxia that is associated with breast cancer metastasis and patient mortality. Previously, we demonstrated that HIF-1 stimulates the expression and activity of TAZ, which is a transcriptional effector of the Hippo signali...

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Detalles Bibliográficos
Autores principales:	Xiang, Lisha, Gilkes, Daniele M., Hu, Hongxia, Luo, Weibo, Bullen, John W., Liang, Houjie, Semenza, Gregg L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494903/ https://www.ncbi.nlm.nih.gov/pubmed/26059435

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