RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development

Derailed endolysosomal trafficking is emerging as a widespread feature of aggressive neoplasms. However, the oncogenic signals that alter membrane homeostasis and their specific contribution to cancer progression remain unclear. Understanding the upstream drivers and downstream regulators of aberran...

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Detalles Bibliográficos
Autores principales: Alonso-Curbelo, Direna, Osterloh, Lisa, Cañón, Estela, Calvo, Tonantzin G., Martínez-Herranz, Raúl, Karras, Panagiotis, Martínez, Sonia, Riveiro-Falkenbach, Erica, Romero, Pablo-Ortiz, Rodríguez-Peralto, José Luis, Pastor, Joaquín, Soengas, María S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494909/
https://www.ncbi.nlm.nih.gov/pubmed/26008978

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