c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression

Breast cancer is a heterogeneous disease with several subtypes carrying unique prognoses. Patients with differentiated luminal tumors experience better outcomes, while effective treatments are unavailable for poorly differentiated tumors, including the basal-like subtype. Mechanisms governing mammar...

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Detalles Bibliográficos
Autores principales: Cantrell, Michael A., Ebelt, Nancy D., Pfefferle, Adam D., Perou, Charles M., Van Den Berg, Carla Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494910/
https://www.ncbi.nlm.nih.gov/pubmed/25970777

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