Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: novel HIF-1-mediated regulation of aquaporins in NP cells

Objectives of this study were to investigate whether AQP1 and AQP5 expression is altered during intervertebral disc degeneration and if hypoxia and HIF-1 regulate their expression in NP cells. AQP expression was measured in human tissues from different degenerative grades; regulation by hypoxia and...

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Detalles Bibliográficos
Autores principales: Johnson, Zariel I., Gogate, Shilpa S., Day, Rebecca, Binch, Abbie, Markova, Dessislava Z., Chiverton, Neil, Cole, Ashley, Conner, Matt, Shapiro, Irving M., Le Maitre, Christine L., Risbud, Makarand V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Pathology: Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494915/
https://www.ncbi.nlm.nih.gov/pubmed/25844601

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