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Identification of a novel TGF-β-miR-122-fibronectin 1/serum response factor signaling cascade and its implication in hepatic fibrogenesis
Transforming growth factor-β (TGF-β) is a potent cytokine that promotes the development of fibrogenic cells, stimulates the expression of fibrosis-related genes, and consequently results in hepatic fibrogenesis. The involvement of miRNAs in this process remains largely unknown. We showed that miR-12...
Autores principales: | Zeng, Chunxian, Wang, Yun-Long, Xie, Chen, Sang, Ye, Li, Tuan-Jie, Zhang, Min, Wang, Ruizhi, Zhang, Qi, Zheng, Limin, Zhuang, Shi-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494934/ https://www.ncbi.nlm.nih.gov/pubmed/25909171 |
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