Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis

Though discovered over four decades ago, the function of N-terminal methylation has mostly remained a mystery. Our discovery of the first mammalian N-terminal methyltransferase, NRMT1, has led to the discovery of many new functions for N-terminal methylation, including regulation of DNA/protein inte...

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Detalles Bibliográficos
Autores principales: Bonsignore, Lindsay A., Butler, Jill Sergesketter, Klinge, Carolyn M., Tooley, Christine E. Schaner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494936/
https://www.ncbi.nlm.nih.gov/pubmed/25909287

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