Cargando…

The prognostic value of the stem-like group in colorectal cancer using a panel of immunohistochemistry markers

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the Western world. It is becoming increasingly clear that CRC is a diverse disease, as exemplified by the identification of subgroups of CRC tumours that are driven by distinct biology. Recently, a number of studies have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ong, Chee Wee, Chong, Pei Yi, McArt, Darragh G., Chan, Jason Yongsheng, Tan, Hwee Tong, Kumar, Alan Prem, Chung, Maxey C. M., Clément, Marie-Véronique, Soong, Richie, Van Schaeybroeck, Sandra, Waugh, David J. J., Johnston, Patrick G., Dunne, Philip D., Salto-Tellez, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Clinical Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494972/ https://www.ncbi.nlm.nih.gov/pubmed/25906747

Ejemplares similares

Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer
por: Hutchinson, Ryan A, et al.
Publicado: (2015)

Connectivity Mapping for Candidate Therapeutics Identification Using Next Generation Sequencing RNA-Seq Data
por: McArt, Darragh G., et al.
Publicado: (2013)

cudaMap: a GPU accelerated program for gene expression connectivity mapping
por: McArt, Darragh G, et al.
Publicado: (2013)

Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer
por: Dunne, Philip D., et al.
Publicado: (2016)

Embracing an integromic approach to tissue biomarker research in cancer: Perspectives and lessons learned
por: Li, Gerald, et al.
Publicado: (2017)

Translation of tissue-based artificial intelligence into clinical practice: from discovery to adoption
por: Geaney, Alice, et al.
Publicado: (2023)

Validation of Next Generation Sequencing Technologies in Comparison to Current Diagnostic Gold Standards for BRAF, EGFR and KRAS Mutational Analysis
por: McCourt, Clare M., et al.
Publicado: (2013)

Identification of Candidate Small-Molecule Therapeutics to Cancer by Gene-Signature Perturbation in Connectivity Mapping
por: McArt, Darragh G., et al.
Publicado: (2011)

Transcriptional upregulation of c-MET is associated with invasion and tumor budding in colorectal cancer
por: Bradley, Conor A., et al.
Publicado: (2016)

Quantification of HER2 heterogeneity in breast cancer–implications for identification of sub-dominant clones for personalised treatment
por: Buckley, Niamh E., et al.
Publicado: (2016)

Delivering a research‐enabled multistakeholder partnership for enhanced patient care at a population level: The Northern Ireland Comprehensive Cancer Program
por: Lawler, Mark, et al.
Publicado: (2015)

Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer
por: Riley, J S, et al.
Publicado: (2013)

QuPath: Open source software for digital pathology image analysis
por: Bankhead, Peter, et al.
Publicado: (2017)

NUQA: Estimating Cancer Spatial and Temporal Heterogeneity and Evolution through Alignment-Free Methods
por: Roddy, Aideen C, et al.
Publicado: (2019)

Transcriptional Profiling of a Patient-Matched Cohort of Glioblastoma (IDH-Wildtype) for Therapeutic Target and Repurposing Drug Identification
por: Roddy, Aideen C., et al.
Publicado: (2023)

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.
por: D'Costa, Zenobia C., et al.
Publicado: (2014)

Transcriptional Subtyping and CD8 Immunohistochemistry Identifies Patients With Stage II and III Colorectal Cancer With Poor Prognosis Who Benefit From Adjuvant Chemotherapy
por: Allen, Wendy L., et al.
Publicado: (2018)

Evolutionary genetic algorithm identifies IL2RB as a potential predictive biomarker for immune-checkpoint therapy in colorectal cancer
por: Alderdice, Matthew, et al.
Publicado: (2021)

Molecular classification of non-invasive breast lesions for personalised therapy and chemoprevention
por: Buckley, Niamh, et al.
Publicado: (2015)

Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer
por: Turkington, R C, et al.
Publicado: (2014)

KRAS mutant colorectal cancer gene signatures identified angiotensin II receptor blockers as potential therapies
por: Wen, Qing, et al.
Publicado: (2016)

Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapies
por: Wen, Qing, et al.
Publicado: (2015)

Impact of Variable RNA-Sequencing Depth on Gene Expression Signatures and Target Compound Robustness: Case Study Examining Brain Tumor (Glioma) Disease Progression
por: Stupnikov, Alexey, et al.
Publicado: (2018)

Novel deep learning-based solution for identification of prognostic subgroups in liver cancer (Hepatocellular carcinoma)
por: Owens, Alice R., et al.
Publicado: (2021)

A gene signature associated with PTEN activation defines good prognosis intermediate risk prostate cancer cases
por: Ong, Chee W, et al.
Publicado: (2018)

QUADrATiC: scalable gene expression connectivity mapping for repurposing FDA-approved therapeutics
por: O’Reilly, Paul G., et al.
Publicado: (2016)

Prostate cancer heterogeneity assessment with multi-regional sampling and alignment-free methods
por: Murphy, Ross G, et al.
Publicado: (2020)

Automated tumor analysis for molecular profiling in lung cancer
por: Hamilton, Peter W., et al.
Publicado: (2015)

Robustness of differential gene expression analysis of RNA-seq
por: Stupnikov, A., et al.
Publicado: (2021)

Immunohistochemistry Panel for Differential Diagnosis of Basal Cell Carcinoma and Trichoblastoma
por: Vega Memije, Maria Elisa, et al.
Publicado: (2014)

Particle swarm optimization artificial intelligence technique for gene signature discovery in transcriptomic cohorts
por: Murphy, Ross G., et al.
Publicado: (2022)

Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification
por: Dunne, Philip D., et al.
Publicado: (2017)

A time for every purpose: using time-dependent sensitivity analysis to help understand and manage dynamic ecological systems
por: Ng, Wee Hao, et al.
Publicado: (2023)

Prognostic ability of a panel of immunohistochemistry markers – retailoring of an 'old solution'
por: Brennan, Donal J, et al.
Publicado: (2008)

Automated Tumour Recognition and Digital Pathology Scoring Unravels New Role for PD-L1 in Predicting Good Outcome in ER-/HER2+ Breast Cancer
por: Humphries, Matthew P., et al.
Publicado: (2018)

IHC-based subcellular quantification provides new insights into prognostic relevance of FLIP and procaspase-8 in non-small-cell lung cancer
por: Hutchinson, Ryan A, et al.
Publicado: (2017)

Genetic factors associated with intestinal metaplasia in a high risk Singapore-Chinese population: a cohort study
por: Zhu, Feng, et al.
Publicado: (2009)

Prolyl isomerase Pin1 down-regulates tumor suppressor RUNX3 in breast cancer
por: Tsang, Ying-Hung Nicole, et al.
Publicado: (2012)

ICOSeg: Real-Time ICOS Protein Expression Segmentation from Immunohistochemistry Slides Using a Lightweight Conv-Transformer Network
por: Singh, Vivek Kumar, et al.
Publicado: (2022)

Modern immunohistochemistry
por: Chu, Peiguo G.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_gk1melcav80qc5mobf0ckddev3