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Cell-Autonomous Regulation of Mu-Opioid Receptor Recycling by Substance P

How neurons coordinate and reprogram multiple neurotransmitter signals is an area of broad interest. Here, we show that substance P (SP), a neuropep-tide associated with inflammatory pain, reprograms opioid receptor recycling and signaling. SP, through activation of the neurokinin 1 (NK1R) receptor,...

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Detalles Bibliográficos
Autores principales: Bowman, Shanna L., Soohoo, Amanda L., Shiwarski, Daniel J., Schulz, Stefan, Pradhan, Amynah A., Puthenveedu, Manojkumar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494997/
https://www.ncbi.nlm.nih.gov/pubmed/25801029
http://dx.doi.org/10.1016/j.celrep.2015.02.045

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