SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity

Gallic acid has been covalently conjugated to SBA-15 mesoporous silica surface through different linkers. Cytotoxic activity of the hybrid organic-inorganic systems against HeLa and KB cell lines has been analyzed. Up to 67% of HeLa or KB tumor cells growth inhibition has been achieved at low silica...

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Autores principales: Lewandowski, Dawid, Ruszkowski, Piotr, Pińska, Anita, Schroeder, Grzegorz, Kurczewska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495030/
https://www.ncbi.nlm.nih.gov/pubmed/26151908
http://dx.doi.org/10.1371/journal.pone.0132541
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author Lewandowski, Dawid
Ruszkowski, Piotr
Pińska, Anita
Schroeder, Grzegorz
Kurczewska, Joanna
author_facet Lewandowski, Dawid
Ruszkowski, Piotr
Pińska, Anita
Schroeder, Grzegorz
Kurczewska, Joanna
author_sort Lewandowski, Dawid
collection PubMed
description Gallic acid has been covalently conjugated to SBA-15 mesoporous silica surface through different linkers. Cytotoxic activity of the hybrid organic-inorganic systems against HeLa and KB cell lines has been analyzed. Up to 67% of HeLa or KB tumor cells growth inhibition has been achieved at low silica concentration used (10 μg mL(-1)).
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spelling pubmed-44950302015-07-15 SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity Lewandowski, Dawid Ruszkowski, Piotr Pińska, Anita Schroeder, Grzegorz Kurczewska, Joanna PLoS One Research Article Gallic acid has been covalently conjugated to SBA-15 mesoporous silica surface through different linkers. Cytotoxic activity of the hybrid organic-inorganic systems against HeLa and KB cell lines has been analyzed. Up to 67% of HeLa or KB tumor cells growth inhibition has been achieved at low silica concentration used (10 μg mL(-1)). Public Library of Science 2015-07-07 /pmc/articles/PMC4495030/ /pubmed/26151908 http://dx.doi.org/10.1371/journal.pone.0132541 Text en © 2015 Lewandowski et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Lewandowski, Dawid
Ruszkowski, Piotr
Pińska, Anita
Schroeder, Grzegorz
Kurczewska, Joanna
SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity
title SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity
title_full SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity
title_fullStr SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity
title_full_unstemmed SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity
title_short SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity
title_sort sba-15 mesoporous silica modified with gallic acid and evaluation of its cytotoxic activity
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495030/
https://www.ncbi.nlm.nih.gov/pubmed/26151908
http://dx.doi.org/10.1371/journal.pone.0132541
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