Synthesis of a new series of biologically interesting 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives

ABSTRACT: A series of 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives have been synthesized from isatoic anhydride and 3-(R(2)-amino)-1,4,2-benzodithiazine 1,1-dioxides. Some synthetic limitations are discussed on the basis of q...

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Detalles Bibliográficos
Autores principales: Brzozowski, Zdzisław, Żołnowska, Beata, Sławiński, Jarosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495064/
https://www.ncbi.nlm.nih.gov/pubmed/26166885
http://dx.doi.org/10.1007/s00706-013-1010-y
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author Brzozowski, Zdzisław
Żołnowska, Beata
Sławiński, Jarosław
author_facet Brzozowski, Zdzisław
Żołnowska, Beata
Sławiński, Jarosław
author_sort Brzozowski, Zdzisław
collection PubMed
description ABSTRACT: A series of 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives have been synthesized from isatoic anhydride and 3-(R(2)-amino)-1,4,2-benzodithiazine 1,1-dioxides. Some synthetic limitations are discussed on the basis of quantum chemical calculations performed by use of the Hartree–Fock method. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-44950642015-07-09 Synthesis of a new series of biologically interesting 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives Brzozowski, Zdzisław Żołnowska, Beata Sławiński, Jarosław Monatsh Chem Original Paper ABSTRACT: A series of 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives have been synthesized from isatoic anhydride and 3-(R(2)-amino)-1,4,2-benzodithiazine 1,1-dioxides. Some synthetic limitations are discussed on the basis of quantum chemical calculations performed by use of the Hartree–Fock method. GRAPHICAL ABSTRACT: [Image: see text] Springer Vienna 2013-06-11 2013 /pmc/articles/PMC4495064/ /pubmed/26166885 http://dx.doi.org/10.1007/s00706-013-1010-y Text en © The Author(s) 2013 https://creativecommons.org/licenses/by-nc/2.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Paper
Brzozowski, Zdzisław
Żołnowska, Beata
Sławiński, Jarosław
Synthesis of a new series of biologically interesting 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives
title Synthesis of a new series of biologically interesting 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives
title_full Synthesis of a new series of biologically interesting 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives
title_fullStr Synthesis of a new series of biologically interesting 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives
title_full_unstemmed Synthesis of a new series of biologically interesting 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives
title_short Synthesis of a new series of biologically interesting 6′-chloro-1′,1′-dioxospiro[4H-benzo[d][1,3,7]oxadiazocine-4,3′(2′H)-[1,4,2]benzodithiazine]-2,6(1H,5H)dione derivatives
title_sort synthesis of a new series of biologically interesting 6′-chloro-1′,1′-dioxospiro[4h-benzo[d][1,3,7]oxadiazocine-4,3′(2′h)-[1,4,2]benzodithiazine]-2,6(1h,5h)dione derivatives
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495064/
https://www.ncbi.nlm.nih.gov/pubmed/26166885
http://dx.doi.org/10.1007/s00706-013-1010-y
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AT sławinskijarosław synthesisofanewseriesofbiologicallyinteresting6chloro11dioxospiro4hbenzod137oxadiazocine432h142benzodithiazine261h5hdionederivatives

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