The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency

Antiretroviral therapy (ART) inhibits HIV-1 replication, but the virus persists in latently infected resting memory CD4(+) T cells susceptible to viral reactivation. The virus-encoded early gene product Tat activates transcription of the viral genome and promotes exponential viral production. Here w...

Descripción completa

Detalles Bibliográficos
Autores principales: Mousseau, Guillaume, Kessing, Cari F., Fromentin, Rémi, Trautmann, Lydie, Chomont, Nicolas, Valente, Susana T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495168/
https://www.ncbi.nlm.nih.gov/pubmed/26152583
http://dx.doi.org/10.1128/mBio.00465-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495168/
https://www.ncbi.nlm.nih.gov/pubmed/26152583
http://dx.doi.org/10.1128/mBio.00465-15

Ejemplares similares