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The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency
Antiretroviral therapy (ART) inhibits HIV-1 replication, but the virus persists in latently infected resting memory CD4(+) T cells susceptible to viral reactivation. The virus-encoded early gene product Tat activates transcription of the viral genome and promotes exponential viral production. Here w...
Autores principales: | Mousseau, Guillaume, Kessing, Cari F., Fromentin, Rémi, Trautmann, Lydie, Chomont, Nicolas, Valente, Susana T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495168/ https://www.ncbi.nlm.nih.gov/pubmed/26152583 http://dx.doi.org/10.1128/mBio.00465-15 |
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