Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells

Transcription factor-mediated reprograming is a powerful method to study cell fate changes. In this study, we demonstrate that the transcription factor Gata6 can initiate reprograming of multiple cell types to induced extraembryonic endoderm stem (iXEN) cells. Intriguingly, Gata6 is sufficient to dr...

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Detalles Bibliográficos
Autores principales: Wamaitha, Sissy E., del Valle, Ignacio, Cho, Lily T.Y., Wei, Yingying, Fogarty, Norah M.E., Blakeley, Paul, Sherwood, Richard I., Ji, Hongkai, Niakan, Kathy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495396/
https://www.ncbi.nlm.nih.gov/pubmed/26109048
http://dx.doi.org/10.1101/gad.257071.114

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