Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells

Mutant p53 impacts the expression of numerous genes at the level of transcription to mediate oncogenesis. We identified vascular endothelial growth factor receptor 2 (VEGFR2), the primary functional VEGF receptor that mediates endothelial cell vascularization, as a mutant p53 transcriptional target...

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Detalles Bibliográficos
Autores principales: Pfister, Neil T., Fomin, Vitalay, Regunath, Kausik, Zhou, Jeffrey Y., Zhou, Wen, Silwal-Pandit, Laxmi, Freed-Pastor, William A., Laptenko, Oleg, Neo, Suat Peng, Bargonetti, Jill, Hoque, Mainul, Tian, Bin, Gunaratne, Jayantha, Engebraaten, Olav, Manley, James L., Børresen-Dale, Anne-Lise, Neilsen, Paul M., Prives, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495400/
https://www.ncbi.nlm.nih.gov/pubmed/26080815
http://dx.doi.org/10.1101/gad.263202.115

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