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Structure–function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2

Cells use specific mechanisms such as histone chaperones to abrogate the inherent barrier that the nucleosome poses to transcribing polymerases. The current model postulates that nucleosomes can be transiently disrupted to accommodate passage of RNA polymerases and that histones H3 and H4 possess th...

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Detalles Bibliográficos
Autores principales: Chen, Shoudeng, Rufiange, Anne, Huang, Hongda, Rajashankar, Kanagalaghatta R., Nourani, Amine, Patel, Dinshaw J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495402/
https://www.ncbi.nlm.nih.gov/pubmed/26109053
http://dx.doi.org/10.1101/gad.261115.115