The saponin DT-13 Attenuates Tumor Necrosis Factor-α-induced Vascular Inflammation Associated with Src/NF-кB/MAPK Pathway Modulation

This study aimed to explore the effect of DT-13 (25(R,S)-ruscogenin- 1-O- [β-d-glucopyranosyl- (1→2)][β-d-xylopyranosyl-(1→3)]-β -d- fucopyranoside) on tumor necrosis factor (TNF)-α-induced vascular inflammation and the potential molecular mechanisms. In vitro, DT-13 suppressed TNF-α-induced adhesio...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanyuan, Sun, Minhui, Han, Yuwei, Zhai, Kefeng, Tang, Youmei, Qin, Xiaoying, Cao, Zhengyu, Yu, Boyang, Kou, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495414/
https://www.ncbi.nlm.nih.gov/pubmed/26157351
http://dx.doi.org/10.7150/ijbs.11635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495414/
https://www.ncbi.nlm.nih.gov/pubmed/26157351
http://dx.doi.org/10.7150/ijbs.11635

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