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The saponin DT-13 Attenuates Tumor Necrosis Factor-α-induced Vascular Inflammation Associated with Src/NF-кB/MAPK Pathway Modulation
This study aimed to explore the effect of DT-13 (25(R,S)-ruscogenin- 1-O- [β-d-glucopyranosyl- (1→2)][β-d-xylopyranosyl-(1→3)]-β -d- fucopyranoside) on tumor necrosis factor (TNF)-α-induced vascular inflammation and the potential molecular mechanisms. In vitro, DT-13 suppressed TNF-α-induced adhesio...
Autores principales: | Zhang, Yuanyuan, Sun, Minhui, Han, Yuwei, Zhai, Kefeng, Tang, Youmei, Qin, Xiaoying, Cao, Zhengyu, Yu, Boyang, Kou, Junping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495414/ https://www.ncbi.nlm.nih.gov/pubmed/26157351 http://dx.doi.org/10.7150/ijbs.11635 |
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