Cargando…
quantro: a data-driven approach to guide the choice of an appropriate normalization method
Normalization is an essential step in the analysis of high-throughput data. Multi-sample global normalization methods, such as quantile normalization, have been successfully used to remove technical variation. However, these methods rely on the assumption that observed global changes across samples...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495646/ https://www.ncbi.nlm.nih.gov/pubmed/26040460 http://dx.doi.org/10.1186/s13059-015-0679-0 |