PAX5-KIAA1549L: a novel fusion gene in a case of pediatric B-cell precursor acute lymphoblastic leukemia

BACKGROUND: In B-cell precursor acute lymphoblastic leukemia (BCP-ALL) PAX5, a transcription factor pivotal for B-cell commitment and maintenance, is frequently affected by genetic alterations. In 2-3 % of the cases PAX5 rearrangements result in the expression of oncogenic fusion genes. The encoded...

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Detalles Bibliográficos
Autores principales: Anderl, Stefanie, König, Margit, Attarbaschi, Andishe, Strehl, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495688/
https://www.ncbi.nlm.nih.gov/pubmed/26157485
http://dx.doi.org/10.1186/s13039-015-0138-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495688/
https://www.ncbi.nlm.nih.gov/pubmed/26157485
http://dx.doi.org/10.1186/s13039-015-0138-3

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