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Efficient generation of influenza virus with a mouse RNA polymerase I-driven all-in-one plasmid

BACKGROUND: The current influenza vaccines are effective against seasonal influenza, but cannot be manufactured in a timely manner for a sudden pandemic or to be cost-effective to immunize huge flocks of birds. We propose a novel influenza vaccine composing a bacterial carrier and a plasmid cargo. I...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangmin, Curtiss, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495709/
https://www.ncbi.nlm.nih.gov/pubmed/26093583
http://dx.doi.org/10.1186/s12985-015-0321-5

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