The combined molecular adjuvant CASAC enhances the CD8+ T cell response to a tumor-associated self-antigen in aged, immunosenescent mice

BACKGROUND: Ineffective induction of T cell mediated immunity in older individuals remains a persistent challenge for vaccine development. Thus, there is a need for more efficient and sophisticated adjuvants that will complement novel vaccine strategies for the elderly. To this end, we have investig...

Descripción completa

Detalles Bibliográficos
Autores principales: Tye, Gee Jun, Ioannou, Kyriaki, Amofah, Eunice, Quartey-Papafio, Ruby, Westrop, Samantha J., Krishnamurthy, Pramila, Noble, Alistair, Harrison, Phillip M., Gaensler, Karin M.L., Barber, Linda D., Farzaneh, Farzin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495856/
https://www.ncbi.nlm.nih.gov/pubmed/26157468
http://dx.doi.org/10.1186/s12979-015-0033-0

Ejemplares similares

Ejemplares similares