Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis

Cyclin D1 is an important molecular driver of human breast cancer but better understanding of its oncogenic mechanisms is needed, especially to enhance efforts in targeted therapeutics. Currently, pharmaceutical initiatives to inhibit cyclin D1 are focused on the catalytic component since the transf...

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Detalles Bibliográficos
Autores principales: Casimiro, Mathew C., Di Sante, Gabriele, Crosariol, Marco, Loro, Emanuele, Dampier, William, Ertel, Adam, Yu, Zuoren, Saria, Elizabeth A., Papanikolaou, Alexandros, Li, Zhiping, Wang, Chenguang, Addya, Sankar, Lisanti, Michael P., Fortina, Paolo, Cardiff, Robert D., Tozeren, Aydin, Knudsen, Erik S., Arnold, Andrew, Pestell, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496164/
https://www.ncbi.nlm.nih.gov/pubmed/25940700

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