Cargando…
Anti-β(2)-microglobulin monoclonal antibodies overcome bortezomib resistance in multiple myeloma by inhibiting autophagy
Our previous studies showed that anti-β(2)M monoclonal antibodies (mAbs) have strong and direct apoptotic effects on multiple myeloma (MM) cells, suggesting that anti-β(2)M mAbs might be developed as a novel therapeutic agent. In this study, we investigated the anti-MM effects of combination treatme...
Autores principales: | Zhang, Mingjun, He, Jin, Liu, Zhiqiang, Lu, Yong, Zheng, Yuhuan, Li, Haiyan, Xu, Jingda, Liu, Huan, Qian, Jianfei, Orlowski, Robert Z., Kwak, Larry W., Yi, Qing, Yang, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496167/ https://www.ncbi.nlm.nih.gov/pubmed/25895124 |
Ejemplares similares
-
Targeting Human β-Microglobulin with Monoclonal Antibodies in Multiple Myeloma - A Potential in Treatment
por: Zhang, Mingjun, et al.
Publicado: (2016) -
Mature adipocytes in bone marrow protect myeloma cells against chemotherapy through autophagy activation
por: Liu, Zhiqiang, et al.
Publicado: (2015) -
Bone Marrow Stromal Cells Derived MCP-1 Reverses the Inhibitory Effects of Multiple Myeloma Cells on Osteoclastogenesis by Upregulating the RANK Expression
por: Liu, Zhiqiang, et al.
Publicado: (2013) -
Nelfinavir augments proteasome inhibition by bortezomib in myeloma cells and overcomes bortezomib and carfilzomib resistance
por: Kraus, M, et al.
Publicado: (2013) -
Bortezomib Treatment Modulates Autophagy in Multiple Myeloma
por: Di Lernia, Giuseppe, et al.
Publicado: (2020)