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RIPK3 expression in cervical cancer cells is required for PolyIC-induced necroptosis, IL-1α release, and efficient paracrine dendritic cell activation
Previous studies have shown that cervical cancer cells only release low levels of pro-inflammatory cytokines owing to infection with human papillomaviruses. This results in low immunogenicity of the cancer cells. The viral dsRNA analog PolyIC has been suggested as a promising adjuvant for cervical c...
Autores principales: | Schmidt, Susanne V., Seibert, Stefanie, Walch-Rückheim, Barbara, Vicinus, Benjamin, Kamionka, Eva-Maria, Pahne-Zeppenfeld, Jennifer, Solomayer, Erich-Franz, Kim, Yoo-Jin, Bohle, Rainer M., Smola, Sigrun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496172/ https://www.ncbi.nlm.nih.gov/pubmed/25888634 |
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