A novel role for microRNA-129-5p in inhibiting ovarian cancer cell proliferation and survival via direct suppression of transcriptional co-activators YAP and TAZ

Transcriptional co-activator Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are key oncogenes in mammalian cells. Activities of YAP and TAZ are largely restricted by the Hippo tumor suppressor pathway through phosphorylation-ubiquitination mechanisms. The...

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Detalles Bibliográficos
Autores principales: Tan, Guosheng, Cao, Xinping, Dai, Qiangsheng, Zhang, Bing, Huang, Jianwen, Xiong, Shiqiu, Zhang, Yong yu, Chen, Wei, Yang, Jianyong, Li, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496175/
https://www.ncbi.nlm.nih.gov/pubmed/25895125

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