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Macrophages promote benzopyrene-induced tumor transformation of human bronchial epithelial cells by activation of NF-κB and STAT3 signaling in a bionic airway chip culture and in animal models

We investigated the role of macrophages in promoting benzopyrene (BaP)-induced malignant transformation of human bronchial epithelial cells using a BaP-induced tumor transformation model with a bionic airway chip in vitro and in animal models. The bionic airway chip culture data showed that macropha...

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Detalles Bibliográficos
Autores principales:	Li, Encheng, Xu, Zhiyun, Zhao, Hui, Sun, Zhao, Wang, Lei, Guo, Zhe, Zhao, Yang, Gao, Zhancheng, Wang, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496191/ https://www.ncbi.nlm.nih.gov/pubmed/25823926

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