Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization

The expression of members of the Eph family of receptor tyrosine kinases and their ephrin ligands is frequently dysregulated in medulloblastomas. We assessed the expression and functional role of EphB1 in medulloblastoma cell lines and engineered mouse models. mRNA and protein expression profiling s...

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Detalles Bibliográficos
Autores principales: Bhatia, Shilpa, Baig, Nimrah A., Timofeeva, Olga, Pasquale, Elena B., Hirsch, Kellen, MacDonald, Tobey J., Dritschilo, Anatoly, Lee, Yi Chien, Henkemeyer, Mark, Rood, Brian, Jung, Mira, Wang, Xiao-Jing, Kool, Marcel, Rodriguez, Olga, Albanese, Chris, Karam, Sana D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496193/
https://www.ncbi.nlm.nih.gov/pubmed/25879388

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