Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition

Both microtubule and topoisomerase II (Top2) are important anticancer targets and their respective inhibitors are widely used in combination for cancer therapy. However, some combinations could be mutually antagonistic and drug resistance further limits their therapeutic efficacy. Here we report YCH...

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Detalles Bibliográficos
Autores principales: Yi, Jun-Mei, Zhang, Xiao-Fei, Huan, Xia-Juan, Song, Shan-Shan, Wang, Wei, Tian, Qian-Ting, Sun, Yi-Ming, Chen, Yi, Ding, Jian, Wang, Ying-Qing, Yang, Chun-Hao, Miao, Ze-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496195/
https://www.ncbi.nlm.nih.gov/pubmed/25840421

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