Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer

Liver cancer is the second-most frequent cause of cancer death in the world and is highly treatment resistant. We reported previously that inhibition of neddylation pathway with specific NAE inhibitor MLN4924, suppressed the malignant phenotypes of liver cancer. However, during the process, MLN4924...

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Detalles Bibliográficos
Autores principales: Chen, Ping, Hu, Tao, Liang, Yupei, Jiang, Yanan, Pan, Yongfu, Li, Chunjie, Zhang, Ping, Wei, Dongping, Li, Pei, Jeong, Lak Shin, Chu, Yiwei, Qi, Hui, Yang, Meng, Hoffman, Robert M., Dong, Ziming, Jia, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496198/
https://www.ncbi.nlm.nih.gov/pubmed/25797246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496198/
https://www.ncbi.nlm.nih.gov/pubmed/25797246

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